Validation of 4 type-STR analysis for identification of 50 Korean

초록

Short tandem repeat (STR) analysis provides genetic fingerprinting of individuals and is an indispensable technique for forensic human identification. Recently, this technique has been used in social areas, such as the identification of The Korean War, descendants of national merit, and missing children. STR analysis is performed by analyzing iteration number of repeating bases in the human genome, and currently FBI provides the Combined DNA Index System (CODIS) based on DNA databases. Among them, we used the autosomal short tandem repeats of loci D13S317, D16S539, D21S11, and amelogenin to validate this technique for identification. The samples were collected from unrelated 50 Korean individuals, and 4 STR loci of these samples were analyzed by ABI 3130 genetic analyzer. We demonstrated that 47 samples out of 50 were classified completely with only 4 STR markers, and perfect sex identification could be accomplished with amelogenin analysis.

키워드