WATCH-SS: Developing a Trustworthy and Explainable Modular Framework for Detecting Cognitive Impairment from Spontaneous Speech

  • Pugh, Sydney
  • Hill, Matthew
  • Hwang, Sy
  • Wu, Rachel
  • Jang, Kuk
  • 외 5명
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초록

Early detection of cognitive impairment (CI) is critical for timely intervention in Alzheimer's disease and AD-related dementias. To address this, we propose the Warning Assessment and Alerting Tool for Cognitive Health from Spontaneous Speech (WATCH-SS), a modular and explainable three-stage framework for detecting CI from a patient's speech sample. The framework uses detectors for five linguistic and acoustic indicators of CI, aggregates their outputs into a set of clinically interpretable summary features, and uses a predictive model for CI classification. We consider multiple approaches to implementing these detectors that range from simple, computationally efficient methods suitable for real-time analysis to strong, resource-intensive methods, better for high accuracy offline analysis. On the DementiaBank ADReSS dataset, WATCH-SS achieved strong predictive performance (AUC = 80% on the test set). This work demonstrates that a modular, feature-based approach can achieve strong performance while providing a transparent diagnostic profile, representing a significant step towards a trustworthy and clinically-usable screening tool for primary care.

키워드

cognitive impairmentAlzheimer's diseasedementianatural language processinglarge language modelmachine learningALZHEIMERS-DISEASEDEMENTIARECOGNITION
제목
WATCH-SS: Developing a Trustworthy and Explainable Modular Framework for Detecting Cognitive Impairment from Spontaneous Speech
저자
Pugh, SydneyHill, MatthewHwang, SyWu, RachelJang, KukIannone, StacyO'Connor, KarenO'Brien, KyraEaton, EricJohnson, Kevin
발행일
2026
유형
Proceedings Paper
저널명
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
페이지
338 ~ 353